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KMID : 0388420040140010183
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Konkuk Journal of Medical Sciences
2004 Volume.14 No. 1 p.183 ~ p.187
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Idiopathic Hypereosinophilic Syndrome Presenting As a Multiple Mass in the Liver
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Choi Seungo-O
Yeon Kyu-Min
Lee Seung-Min
Kim Soon-Je
Wang Joon-Ho
Park Hyung-Seok
Lee Jae-Dong
Jin Chun-Jo
Lee Chang-Hoon
Shin Hyun-Joon
Kim Jeong-Eun
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Abstract
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Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.
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KEYWORD
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Hypereosinophilic syndrome, eosinophilia, hepatic involvement
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